The dual role of thiourea in the thiotrifluoromethylation of alkenes

Alkenes substituted with a thiourea undergo C–CF(3) followed by intramolecular C–S bond formation with the Togni reagent and trifluoroacetic acid (TFA) at room temperature; thiols and thioamides are not suitable S-sources for this reaction. This anti-addition process involves a CF(3) radical, and af...

Descripción completa

Detalles Bibliográficos
Autores principales: Ricci, Paolo, Khotavivattana, Tanatorn, Pfeifer, Lukas, Médebielle, Maurice, Morphy, John Richard, Gouverneur, Véronique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2017
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5369526/
https://www.ncbi.nlm.nih.gov/pubmed/28451260
http://dx.doi.org/10.1039/c6sc02790c

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5369526/
https://www.ncbi.nlm.nih.gov/pubmed/28451260
http://dx.doi.org/10.1039/c6sc02790c

Ejemplares similares