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The dual role of thiourea in the thiotrifluoromethylation of alkenes
Alkenes substituted with a thiourea undergo C–CF(3) followed by intramolecular C–S bond formation with the Togni reagent and trifluoroacetic acid (TFA) at room temperature; thiols and thioamides are not suitable S-sources for this reaction. This anti-addition process involves a CF(3) radical, and af...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Royal Society of Chemistry
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5369526/ https://www.ncbi.nlm.nih.gov/pubmed/28451260 http://dx.doi.org/10.1039/c6sc02790c |