Cargando…

Micro-flow photosynthesis of new dienophiles for inverse-electron-demand Diels–Alder reactions. Potential applications for pretargeted in vivo PET imaging

Pretargeted PET imaging has emerged as an effective two-step in vivo approach that combines the superior affinity and selectivity of antibodies with the rapid pharmacokinetics and favorable dosimetry of smaller molecules radiolabeled with short-lived radionuclides. This approach can be based on the...

Descripción completa

Detalles Bibliográficos
Autores principales: Billaud, Emilie M. F., Shahbazali, Elnaz, Ahamed, Muneer, Cleeren, Frederik, Noël, Timothy, Koole, Michel, Verbruggen, Alfons, Hessel, Volker, Bormans, Guy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5369547/
https://www.ncbi.nlm.nih.gov/pubmed/28451267
http://dx.doi.org/10.1039/c6sc02933g