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On-treatment HBV DNA dynamics predict virological breakthrough in entecavir-treated HBeAg-positive chronic hepatitis B

BACKGROUND & AIMS: Virological breakthrough (VBT) could be a manifestation of chronic hepatitis B (CHB) in patients treated with long-term nucleot(s)ide analogues. We aimed to determine the association of on-treatment serum hepatitis B virus (HBV) DNA with VBT in HBeAg-positive CHB patients rece...

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Detalles Bibliográficos
Autores principales: Huang, Yi-Jie, Chang, Chi-Sen, Peng, Yen-Chun, Yeh, Hong-Zen, Yang, Sheng-Shun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5369759/
https://www.ncbi.nlm.nih.gov/pubmed/28350873
http://dx.doi.org/10.1371/journal.pone.0174046