Differential recruitment efficacy of patient-derived amyloidogenic and myeloma light chain proteins by synthetic fibrils—A metric for predicting amyloid propensity

BACKGROUND: Monoclonal free light chain (LC) proteins are present in the circulation of patients with immunoproliferative disorders such as light chain (AL) amyloidosis and multiple myeloma (MM). Light chain-associated amyloid is a complex pathology composed of proteinaceous fibrils and extracellula...

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Detalles Bibliográficos
Autores principales: Martin, Emily B., Williams, Angela, Wooliver, Craig, Heidel, R. Eric, Adams, Sarah, Dunlap, John, Ramirez-Alvarado, Marina, Blancas-Mejia, Luis M., Lands, Ronald H., Kennel, Stephen J., Wall, Jonathan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5369765/
https://www.ncbi.nlm.nih.gov/pubmed/28350808
http://dx.doi.org/10.1371/journal.pone.0174152

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5369765/
https://www.ncbi.nlm.nih.gov/pubmed/28350808
http://dx.doi.org/10.1371/journal.pone.0174152

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