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Differential recruitment efficacy of patient-derived amyloidogenic and myeloma light chain proteins by synthetic fibrils—A metric for predicting amyloid propensity
BACKGROUND: Monoclonal free light chain (LC) proteins are present in the circulation of patients with immunoproliferative disorders such as light chain (AL) amyloidosis and multiple myeloma (MM). Light chain-associated amyloid is a complex pathology composed of proteinaceous fibrils and extracellula...
Autores principales: | Martin, Emily B., Williams, Angela, Wooliver, Craig, Heidel, R. Eric, Adams, Sarah, Dunlap, John, Ramirez-Alvarado, Marina, Blancas-Mejia, Luis M., Lands, Ronald H., Kennel, Stephen J., Wall, Jonathan S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5369765/ https://www.ncbi.nlm.nih.gov/pubmed/28350808 http://dx.doi.org/10.1371/journal.pone.0174152 |
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