Sensitizing thermochemotherapy with a PARP1-inhibitor

Cis-diamminedichloroplatinum(II) (cisplatin, cDDP) is an effective chemotherapeutic agent that induces DNA double strand breaks (DSBs), primarily in replicating cells. Generally, such DSBs can be repaired by the classical or backup non-homologous end joining (c-NHEJ/b-NHEJ) or homologous recombinati...

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Detalles Bibliográficos
Autores principales: Oei, Arlene L, Vriend, Lianne E.M, van Leeuwen, Caspar M., Rodermond, Hans M, Cate, Rosemarie ten, Westermann, Anneke M, Stalpers, Lukas J.A., Crezee, Johannes, Kanaar, Roland, Petra, Kok H., Krawczyk, Przemek M, Franken, Nicolaas A.P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5369964/
https://www.ncbi.nlm.nih.gov/pubmed/27557507
http://dx.doi.org/10.18632/oncotarget.11422

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5369964/
https://www.ncbi.nlm.nih.gov/pubmed/27557507
http://dx.doi.org/10.18632/oncotarget.11422

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