Variations within 3′-UTR of MDM4 gene contribute to clinical outcomes of advanced non-small cell lung cancer patients following platinum-based chemotherapy

Single-nucleotide polymorphism (SNPs) in microRNA (miRNA)-binding sites may modulate the posttranscriptional regulation of gene expression and explain individual sensitivity to platinum agents. This study aimed to investigate the impact of SNPs located at 3′-untranslated region (UTR) of MDM4 gene, o...

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Detalles Bibliográficos
Autores principales: Yang, Yang, Gao, Wen, Ding, Xi, Xu, Wen, Liu, Di, Su, Bo, Sun, Yifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5369965/
https://www.ncbi.nlm.nih.gov/pubmed/27462918
http://dx.doi.org/10.18632/oncotarget.10771

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5369965/
https://www.ncbi.nlm.nih.gov/pubmed/27462918
http://dx.doi.org/10.18632/oncotarget.10771

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