Near infrared fluorescent imaging of choline kinase alpha expression and inhibition in breast tumors

Choline kinase alpha (ChoKα) overexpression is associated with an aggressive tumor phenotype. ChoKα inhibitors induce apoptosis in tumors, however validation of their specificity is difficult in vivo. We report the use of optical imaging to assess ChoKα status in cells and in vivo using JAS239, a ca...

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Detalles Bibliográficos
Autores principales: Arlauckas, Sean P., Kumar, Manoj, Popov, Anatoliy V., Poptani, Harish, Delikatny, Edward J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5369982/
https://www.ncbi.nlm.nih.gov/pubmed/28157707
http://dx.doi.org/10.18632/oncotarget.14965

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5369982/
https://www.ncbi.nlm.nih.gov/pubmed/28157707
http://dx.doi.org/10.18632/oncotarget.14965

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