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Elucidation of the genetic and epigenetic landscape alterations in RNA binding proteins in glioblastoma

RNA binding proteins (RBPs) have been implicated in cancer development. An integrated bioinformatics analysis of RBPs (n = 1756) in various datasets (n = 11) revealed several genetic and epigenetically altered events among RBPs in glioblastoma (GBM). We identified 13 mutated and 472 differentially r...

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Detalles Bibliográficos
Autores principales: Bhargava, Shruti, Patil, Vikas, Mahalingam, Kulandaivelu, Somasundaram, Kumaravel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5369992/
https://www.ncbi.nlm.nih.gov/pubmed/28035070
http://dx.doi.org/10.18632/oncotarget.14287