Genetic variants in the TGFβ-signaling pathway influence expression of miRNAs in colon and rectal normal mucosa and tumor tissue

The TGF-β signaling pathway is involved in regulation of cell growth, angiogenesis, and metastasis. We test the hypothesis that genetic variation in the TGF-β signaling pathway alters miRNA expression. We use data from 1188 colorectal cancer cases to evaluate associations between 80 SNPs in 21 genes...

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Detalles Bibliográficos
Autores principales: Slattery, Martha L., Trivellas, Andromahi, Pellatt, Andrew J., Mullany, Lila E., Stevens, John R., Wolff, Roger K., Herrick, Jennifer S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5370000/
https://www.ncbi.nlm.nih.gov/pubmed/28061442
http://dx.doi.org/10.18632/oncotarget.14508

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5370000/
https://www.ncbi.nlm.nih.gov/pubmed/28061442
http://dx.doi.org/10.18632/oncotarget.14508

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