Biological functions of CDK5 and potential CDK5 targeted clinical treatments

Cyclin dependent kinases are proline-directed serine/threonine protein kinases that are traditionally activated upon association with a regulatory subunit. For most CDKs, activation by a cyclin occurs through association and phosphorylation of the CDK’s T-loop. CDK5 is unusual because it is not typi...

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Detalles Bibliográficos
Autores principales: Shupp, Alison, Casimiro, Mathew C., Pestell, Richard G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5370047/
https://www.ncbi.nlm.nih.gov/pubmed/28077789
http://dx.doi.org/10.18632/oncotarget.14538

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5370047/
https://www.ncbi.nlm.nih.gov/pubmed/28077789
http://dx.doi.org/10.18632/oncotarget.14538

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