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Anti-RhoC siRNAs inhibit the proliferation and invasiveness of breast cancer cells via modulating the KAI1, MMP9, and CXCR4 expression

Overexpression of RhoC in breast cancer cells indicates poor prognosis. In the present study, we aim to investigate the possible antitumor effects of anti-RhoC small-interfering RNA (siRNA) in inflammatory breast cancer cells. In this study, a specific anti-RhoC siRNA was used to inhibit RhoC synthe...

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Detalles Bibliográficos
Autores principales: Xu, Xu-Dong, Shen, Han-Bin, Zhu, Li, Lu, Jian-Qin, Zhang, Lin, Luo, Zhi-Yong, Wu, Ya-Qun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5370064/
https://www.ncbi.nlm.nih.gov/pubmed/28367066
http://dx.doi.org/10.2147/OTT.S93164