Exposure to atheroma-relevant 7-oxysterols causes proteomic alterations in cell death, cellular longevity, and lipid metabolism in THP-1 macrophages

The 7-oxysterols are recognised as strong enhancers of inflammatory processes in foamy macrophages. Atheroma-relevant 7-oxysterol mixtures induce a mixed type of cell death in macrophages, and trigger cellular oxidative stress responses, which mimic oxidative exposures observed in atherosclerotic le...

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Detalles Bibliográficos
Autores principales: Ward, Liam J., Ljunggren, Stefan A., Karlsson, Helen, Li, Wei, Yuan, Xi-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5370125/
https://www.ncbi.nlm.nih.gov/pubmed/28350877
http://dx.doi.org/10.1371/journal.pone.0174475

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5370125/
https://www.ncbi.nlm.nih.gov/pubmed/28350877
http://dx.doi.org/10.1371/journal.pone.0174475

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