The prevalence, penetrance, and expressivity of etiologic IRF6 variants in orofacial clefts patients from sub‐Saharan Africa

BACKGROUND: Orofacial clefts are congenital malformations of the orofacial region, with a global incidence of one per 700 live births. Interferon Regulatory Factor 6 (IRF6) (OMIM:607199) gene has been associated with the etiology of both syndromic and nonsyndromic orofacial clefts. The aim of this s...

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Detalles Bibliográficos
Autores principales: Gowans, Lord Jephthah Joojo, Busch, Tamara D., Mossey, Peter A., Eshete, Mekonen A., Adeyemo, Wasiu L., Aregbesola, Babatunde, Donkor, Peter, Arthur, Fareed K. N., Agbenorku, Pius, Olutayo, James, Twumasi, Peter, Braimah, Rahman, Oti, Alexander A., Plange‐Rhule, Gyikua, Obiri‐Yeboah, Solomon, Abate, Fikre, Hoyte‐Williams, Paa E., Hailu, Taye, Murray, Jeffrey C., Butali, Azeez
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5370218/
https://www.ncbi.nlm.nih.gov/pubmed/28361103
http://dx.doi.org/10.1002/mgg3.273

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5370218/
https://www.ncbi.nlm.nih.gov/pubmed/28361103
http://dx.doi.org/10.1002/mgg3.273

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