Compound 19e, a Novel Glucokinase Activator, Protects against Cytokine-Induced Beta-Cell Apoptosis in INS-1 Cells

Previously, compound 19e, a novel heteroaryl-containing benzamide derivative, was identified as a potent glucokinase activator (GKA) and showed a glucose-lowering effect in diabetic mice. In this study, the anti-apoptotic actions of 19e were evaluated in INS-1 pancreatic beta-cells co-treated with T...

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Detalles Bibliográficos
Autores principales: Oh, Yoon Sin, Seo, Eunhui, Park, Kaapjoo, Jun, Hee-Sook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5370240/
https://www.ncbi.nlm.nih.gov/pubmed/28405188
http://dx.doi.org/10.3389/fphar.2017.00169

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5370240/
https://www.ncbi.nlm.nih.gov/pubmed/28405188
http://dx.doi.org/10.3389/fphar.2017.00169

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