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Divergent Modulation of Nociception by Glutamatergic and GABAergic Neuronal Subpopulations in the Periaqueductal Gray

The ventrolateral periaqueductal gray (vlPAG) constitutes a major descending pain modulatory system and is a crucial site for opioid-induced analgesia. A number of previous studies have demonstrated that glutamate and GABA play critical opposing roles in nociceptive processing in the vlPAG. It has b...

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Detalles Bibliográficos
Autores principales: Samineni, Vijay K., Grajales-Reyes, Jose G., Copits, Bryan A., O’Brien, Daniel E., Trigg, Sarah L., Gomez, Adrian M., Bruchas, Michael R., Gereau, Robert W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5370278/
https://www.ncbi.nlm.nih.gov/pubmed/28374016
http://dx.doi.org/10.1523/ENEURO.0129-16.2017