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Divergent Modulation of Nociception by Glutamatergic and GABAergic Neuronal Subpopulations in the Periaqueductal Gray
The ventrolateral periaqueductal gray (vlPAG) constitutes a major descending pain modulatory system and is a crucial site for opioid-induced analgesia. A number of previous studies have demonstrated that glutamate and GABA play critical opposing roles in nociceptive processing in the vlPAG. It has b...
Autores principales: | Samineni, Vijay K., Grajales-Reyes, Jose G., Copits, Bryan A., O’Brien, Daniel E., Trigg, Sarah L., Gomez, Adrian M., Bruchas, Michael R., Gereau, Robert W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Society for Neuroscience
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5370278/ https://www.ncbi.nlm.nih.gov/pubmed/28374016 http://dx.doi.org/10.1523/ENEURO.0129-16.2017 |
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