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Mechanism Underlying Linezolid-induced Thrombocytopenia in a Chronic Kidney Failure Mouse Model

OBJECTIVE: To investigate the relationship between renal function and linezolid (LZD)-induced thrombocytopenia and elucidate the underlying mechanism using a chronic renal disease (CRD) mouse model. MATERIALS AND METHODS: CRD was induced in 5-week-old male Institute of Cancer Research (ICR) mice by...

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Detalles Bibliográficos
Autores principales: Nishijo, Nao, Tsuji, Yasuhiro, Matsunaga, Kazuhisa, Kutsukake, Masahiko, Okazaki, Fumiyasu, Fukumori, Shiro, Kasai, Hidefumi, Hiraki, Yoichi, Sakamaki, Ippei, Yamamoto, Yoshihiro, Karube, Yoshiharu, To, Hideto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5370331/
https://www.ncbi.nlm.nih.gov/pubmed/28405130
http://dx.doi.org/10.4103/jpp.JPP_167_16