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Inhibition of Proteasome Activity Induces Aggregation of IFIT2 in the Centrosome and Enhances IFIT2-Induced Cell Apoptosis

IFN-induced protein with tetratricopeptide repeats 2 (IFIT2), one of the most highly responsive interferon-stimulated genes, inhibits the proliferation and migration of cancer cells and regulates viral replication. IFIT2 has been demonstrated to be a cytoskeleton-associated protein that becomes enri...

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Detalles Bibliográficos
Autores principales: Chen, Limin, Liu, Shuyuan, Xu, Fen, Kong, Yunyuan, Wan, Lagen, zhang, Yonglu, Zhang, Zhanglin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5370445/
https://www.ncbi.nlm.nih.gov/pubmed/28367102
http://dx.doi.org/10.7150/ijbs.17236