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Dietary restriction protects from age-associated DNA methylation and induces epigenetic reprogramming of lipid metabolism

BACKGROUND: Dietary restriction (DR), a reduction in food intake without malnutrition, increases most aspects of health during aging and extends lifespan in diverse species, including rodents. However, the mechanisms by which DR interacts with the aging process to improve health in old age are poorl...

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Detalles Bibliográficos
Autores principales: Hahn, Oliver, Grönke, Sebastian, Stubbs, Thomas M., Ficz, Gabriella, Hendrich, Oliver, Krueger, Felix, Andrews, Simon, Zhang, Qifeng, Wakelam, Michael J., Beyer, Andreas, Reik, Wolf, Partridge, Linda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5370449/
https://www.ncbi.nlm.nih.gov/pubmed/28351387
http://dx.doi.org/10.1186/s13059-017-1187-1