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Reduced Histone H3 Lysine 9 Methylation Contributes to the Pathogenesis of Latent Autoimmune Diabetes in Adults via Regulation of SUV39H2 and KDM4C

Aims. Latent autoimmune diabetes in adults (LADA) is an autoimmune disease of which the mechanism is not clear. Emerging evidence suggests that histone methylation contributes to autoimmunity. Methods. Blood CD4(+) T lymphocytes from 26 LADA patients and 26 healthy controls were isolated to detect h...

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Detalles Bibliográficos
Autores principales: Liu, Xi-yu, Li, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5370514/
https://www.ncbi.nlm.nih.gov/pubmed/28396876
http://dx.doi.org/10.1155/2017/8365762