Use of whole-genome sequencing to distinguish relapse from reinfection in a completed tuberculosis clinical trial

BACKGROUND: RIFAQUIN was a tuberculosis chemotherapy trial in southern Africa including regimens with high-dose rifapentine with moxifloxacin. Here, the application of whole-genome sequencing (WGS) is evaluated within RIFAQUIN for identifying new infections in treated patients as either relapses or...

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Detalles Bibliográficos
Autores principales: Witney, Adam A., Bateson, Anna L. E., Jindani, Amina, Phillips, Patrick P. J., Coleman, David, Stoker, Neil G., Butcher, Philip D., McHugh, Timothy D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5371199/
https://www.ncbi.nlm.nih.gov/pubmed/28351427
http://dx.doi.org/10.1186/s12916-017-0834-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5371199/
https://www.ncbi.nlm.nih.gov/pubmed/28351427
http://dx.doi.org/10.1186/s12916-017-0834-4

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