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Genome-wide methylation analysis identifies a core set of hypermethylated genes in CIMP-H colorectal cancer
BACKGROUND: Aberrant DNA methylation profiles are a characteristic of all known cancer types, epitomized by the CpG island methylator phenotype (CIMP) in colorectal cancer (CRC). Hypermethylation has been observed at CpG islands throughout the genome, but it is unclear which factors determine whethe...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5371203/ https://www.ncbi.nlm.nih.gov/pubmed/28351398 http://dx.doi.org/10.1186/s12885-017-3226-4 |