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Genome-wide methylation analysis identifies a core set of hypermethylated genes in CIMP-H colorectal cancer

BACKGROUND: Aberrant DNA methylation profiles are a characteristic of all known cancer types, epitomized by the CpG island methylator phenotype (CIMP) in colorectal cancer (CRC). Hypermethylation has been observed at CpG islands throughout the genome, but it is unclear which factors determine whethe...

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Detalles Bibliográficos
Autores principales:	McInnes, Tyler, Zou, Donghui, Rao, Dasari S., Munro, Francesca M., Phillips, Vicky L., McCall, John L., Black, Michael A., Reeve, Anthony E., Guilford, Parry J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5371203/ https://www.ncbi.nlm.nih.gov/pubmed/28351398 http://dx.doi.org/10.1186/s12885-017-3226-4

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