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The role of stromal cancer-associated fibroblasts in pancreatic cancer

Pancreatic ductal adenocarcinoma (PDAC) is a lethal cancer generally refractory to conventional treatments. Cancer-associated fibroblasts (CAFs) are cellular components of the desmoplastic stroma characteristic to the tumor that contributes to this treatment resistance. Various markers for CAFs have...

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Detalles Bibliográficos
Autores principales: von Ahrens, Dagny, Bhagat, Tushar D., Nagrath, Deepak, Maitra, Anirban, Verma, Amit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5371211/
https://www.ncbi.nlm.nih.gov/pubmed/28351381
http://dx.doi.org/10.1186/s13045-017-0448-5