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Protocol of the PANCALYZE trial: a multicenter, prospective study investigating the tumor biomarkers CXCR4, SMAD4, SOX9 and IFIT3 in patients with resected pancreatic adenocarcinoma to predict the pattern of recurrence of the disease

BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal malignancies today with an urgent need for novel therapeutic strategies. Biomarker analysis helps to better understand tumor biology and might emerge as a tool to develop personalized therapies. The aim of the study is to...

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Detalles Bibliográficos
Autores principales: Popp, Felix C., Popp, Marie Christine, Zhao, Yue, Betzler, Christopher, Kropf, Siegfried, Garlipp, Benjamin, Benckert, Christoph, Kalinski, Thomas, Lippert, Hans, Bruns, Christiane J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5371262/
https://www.ncbi.nlm.nih.gov/pubmed/28356064
http://dx.doi.org/10.1186/s12885-017-3186-8