Surgery increases cell death and induces changes in gene expression compared with anesthesia alone in the developing piglet brain

In a range of animal species, exposure of the brain to general anaesthesia without surgery during early infancy may adversely affect its neural and cognitive development. The mechanisms mediating this are complex but include an increase in brain cell death. In humans, attempts to link adverse cognit...

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Detalles Bibliográficos
Autores principales: Broad, Kevin D., Kawano, Go, Fierens, Igor, Rocha-Ferreira, Eridan, Hristova, Mariya, Ezzati, Mojgan, Rostami, Jamshid, Alonso-Alconada, Daniel, Chaban, Badr, Hassell, Jane, Fleiss, Bobbi, Gressens, Pierre, Sanders, Robert D., Robertson, Nicola J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5371291/
https://www.ncbi.nlm.nih.gov/pubmed/28355229
http://dx.doi.org/10.1371/journal.pone.0173413

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5371291/
https://www.ncbi.nlm.nih.gov/pubmed/28355229
http://dx.doi.org/10.1371/journal.pone.0173413

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