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Surgery increases cell death and induces changes in gene expression compared with anesthesia alone in the developing piglet brain
In a range of animal species, exposure of the brain to general anaesthesia without surgery during early infancy may adversely affect its neural and cognitive development. The mechanisms mediating this are complex but include an increase in brain cell death. In humans, attempts to link adverse cognit...
Autores principales: | Broad, Kevin D., Kawano, Go, Fierens, Igor, Rocha-Ferreira, Eridan, Hristova, Mariya, Ezzati, Mojgan, Rostami, Jamshid, Alonso-Alconada, Daniel, Chaban, Badr, Hassell, Jane, Fleiss, Bobbi, Gressens, Pierre, Sanders, Robert D., Robertson, Nicola J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5371291/ https://www.ncbi.nlm.nih.gov/pubmed/28355229 http://dx.doi.org/10.1371/journal.pone.0173413 |
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