Transient helicity in intrinsically disordered Axin-1 studied by NMR spectroscopy and molecular dynamics simulations

Many natural proteins are, as a whole or in part, intrinsically disordered. Frequently, such intrinsically disordered regions (IDRs) undergo a transition to a defined and often helical conformation upon binding to partner molecules. The intrinsic propensity of an IDR sequence to fold into a helical...

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Detalles Bibliográficos
Autores principales: Bomblies, Rainer, Luitz, Manuel Patrick, Scanu, Sandra, Madl, Tobias, Zacharias, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5371316/
https://www.ncbi.nlm.nih.gov/pubmed/28355271
http://dx.doi.org/10.1371/journal.pone.0174337

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5371316/
https://www.ncbi.nlm.nih.gov/pubmed/28355271
http://dx.doi.org/10.1371/journal.pone.0174337

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