Vitamin D receptor gene is epigenetically altered and transcriptionally up-regulated in multiple sclerosis

OBJECTIVE: Vitamin D deficiency has been linked to increased risk of multiple sclerosis (MS) and poor outcome. However, the specific role that vitamin D plays in MS still remains unknown. In order to identify potential mechanisms underlying vitamin D effects in MS, we profiled epigenetic changes in...

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Detalles Bibliográficos
Autores principales: Ayuso, Teresa, Aznar, Patricia, Soriano, Luis, Olaskoaga, Ander, Roldán, Miren, Otano, María, Ajuria, Iratxe, Soriano, Gerardo, Lacruz, Francisco, Mendioroz, Maite
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5371344/
https://www.ncbi.nlm.nih.gov/pubmed/28355272
http://dx.doi.org/10.1371/journal.pone.0174726

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5371344/
https://www.ncbi.nlm.nih.gov/pubmed/28355272
http://dx.doi.org/10.1371/journal.pone.0174726

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