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Vitamin D receptor gene is epigenetically altered and transcriptionally up-regulated in multiple sclerosis
OBJECTIVE: Vitamin D deficiency has been linked to increased risk of multiple sclerosis (MS) and poor outcome. However, the specific role that vitamin D plays in MS still remains unknown. In order to identify potential mechanisms underlying vitamin D effects in MS, we profiled epigenetic changes in...
Autores principales: | Ayuso, Teresa, Aznar, Patricia, Soriano, Luis, Olaskoaga, Ander, Roldán, Miren, Otano, María, Ajuria, Iratxe, Soriano, Gerardo, Lacruz, Francisco, Mendioroz, Maite |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5371344/ https://www.ncbi.nlm.nih.gov/pubmed/28355272 http://dx.doi.org/10.1371/journal.pone.0174726 |
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