Trypanocidal Effect of Isotretinoin through the Inhibition of Polyamine and Amino Acid Transporters in Trypanosoma cruzi

Polyamines are essential compounds to all living organisms and in the specific case of Trypanosoma cruzi, the causative agent of Chagas disease, they are exclusively obtained through transport processes since this parasite is auxotrophic for polyamines. Previous works reported that retinol acetate i...

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Detalles Bibliográficos
Autores principales: Reigada, Chantal, Valera-Vera, Edward A., Sayé, Melisa, Errasti, Andrea E., Avila, Carla C., Miranda, Mariana R., Pereira, Claudio A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5371382/
https://www.ncbi.nlm.nih.gov/pubmed/28306713
http://dx.doi.org/10.1371/journal.pntd.0005472

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5371382/
https://www.ncbi.nlm.nih.gov/pubmed/28306713
http://dx.doi.org/10.1371/journal.pntd.0005472

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