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Trypanocidal Effect of Isotretinoin through the Inhibition of Polyamine and Amino Acid Transporters in Trypanosoma cruzi
Polyamines are essential compounds to all living organisms and in the specific case of Trypanosoma cruzi, the causative agent of Chagas disease, they are exclusively obtained through transport processes since this parasite is auxotrophic for polyamines. Previous works reported that retinol acetate i...
Autores principales: | Reigada, Chantal, Valera-Vera, Edward A., Sayé, Melisa, Errasti, Andrea E., Avila, Carla C., Miranda, Mariana R., Pereira, Claudio A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5371382/ https://www.ncbi.nlm.nih.gov/pubmed/28306713 http://dx.doi.org/10.1371/journal.pntd.0005472 |
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