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Preclinical mouse model to monitor live Muc5b-producing conjunctival goblet cell density under pharmacological treatments

PURPOSE: Modification of mucous cell density and gel-forming mucin production are established hallmarks of mucosal diseases. Our aim was to develop and validate a mouse model to study live goblet cell density in pathological situations and under pharmacological treatments. METHODS: We created a repo...

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Detalles Bibliográficos
Autores principales: Portal, Céline, Gouyer, Valérie, Gottrand, Frédéric, Desseyn, Jean-Luc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5371386/
https://www.ncbi.nlm.nih.gov/pubmed/28355261
http://dx.doi.org/10.1371/journal.pone.0174764