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Preclinical mouse model to monitor live Muc5b-producing conjunctival goblet cell density under pharmacological treatments
PURPOSE: Modification of mucous cell density and gel-forming mucin production are established hallmarks of mucosal diseases. Our aim was to develop and validate a mouse model to study live goblet cell density in pathological situations and under pharmacological treatments. METHODS: We created a repo...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5371386/ https://www.ncbi.nlm.nih.gov/pubmed/28355261 http://dx.doi.org/10.1371/journal.pone.0174764 |