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Contribution of the Purinergic Receptor P2X7 to Development of Lung Immunopathology during Influenza Virus Infection

An exacerbated immune response is one of the main causes of influenza-induced lung damage during infection. The molecular mechanisms regulating the fate of the initial immune response to infection, either as a protective response or as detrimental immunopathology, are not well understood. The purine...

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Detalles Bibliográficos
Autores principales: Leyva-Grado, Victor H., Ermler, Megan E., Schotsaert, Michael, Gonzalez, Ma G., Gillespie, Virginia, Lim, Jean K., García-Sastre, Adolfo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5371412/
https://www.ncbi.nlm.nih.gov/pubmed/28351919
http://dx.doi.org/10.1128/mBio.00229-17