SpxA1 and SpxA2 Act Coordinately To Fine-Tune Stress Responses and Virulence in Streptococcus pyogenes

SpxA is a unique transcriptional regulator highly conserved among members of the phylum Firmicutes that binds RNA polymerase and can act as an antiactivator. Why some Firmicutes members have two highly similar SpxA paralogs is not understood. Here, we show that the SpxA paralogs of the pathogen Stre...

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Detalles Bibliográficos
Autores principales: Port, Gary C., Cusumano, Zachary T., Tumminello, Paul R., Caparon, Michael G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5371413/
https://www.ncbi.nlm.nih.gov/pubmed/28351920
http://dx.doi.org/10.1128/mBio.00288-17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5371413/
https://www.ncbi.nlm.nih.gov/pubmed/28351920
http://dx.doi.org/10.1128/mBio.00288-17

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