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CdiA Effectors Use Modular Receptor-Binding Domains To Recognize Target Bacteria

Contact-dependent growth inhibition (CDI) systems encode CdiA effectors, which bind to specific receptors on neighboring bacteria and deliver C-terminal toxin domains to suppress target cell growth. Two classes of CdiA effectors that bind distinct cell surface receptors have been identified, but the...

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Detalles Bibliográficos
Autores principales: Ruhe, Zachary C., Nguyen, Josephine Y., Xiong, Jing, Koskiniemi, Sanna, Beck, Christina M., Perkins, Basil R., Low, David A., Hayes, Christopher S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5371414/
https://www.ncbi.nlm.nih.gov/pubmed/28351921
http://dx.doi.org/10.1128/mBio.00290-17