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Differences in Integron Cassette Excision Dynamics Shape a Trade-Off between Evolvability and Genetic Capacitance

Integrons ensure a rapid and “on demand” response to environmental stresses driving bacterial adaptation. They are able to capture, store, and reorder functional gene cassettes due to site-specific recombination catalyzed by their integrase. Integrons can be either sedentary and chromosomally locate...

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Detalles Bibliográficos
Autores principales: Loot, Céline, Nivina, Aleksandra, Cury, Jean, Escudero, José Antonio, Ducos-Galand, Magaly, Bikard, David, Rocha, Eduardo P. C., Mazel, Didier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5371416/
https://www.ncbi.nlm.nih.gov/pubmed/28351923
http://dx.doi.org/10.1128/mBio.02296-16