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Differences in Integron Cassette Excision Dynamics Shape a Trade-Off between Evolvability and Genetic Capacitance
Integrons ensure a rapid and “on demand” response to environmental stresses driving bacterial adaptation. They are able to capture, store, and reorder functional gene cassettes due to site-specific recombination catalyzed by their integrase. Integrons can be either sedentary and chromosomally locate...
Autores principales: | Loot, Céline, Nivina, Aleksandra, Cury, Jean, Escudero, José Antonio, Ducos-Galand, Magaly, Bikard, David, Rocha, Eduardo P. C., Mazel, Didier |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5371416/ https://www.ncbi.nlm.nih.gov/pubmed/28351923 http://dx.doi.org/10.1128/mBio.02296-16 |
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