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Label-free optical detection of single enzyme-reactant reactions and associated conformational changes

Monitoring the kinetics and conformational dynamics of single enzymes is crucial to better understand their biological functions because these motions and structural dynamics are usually unsynchronized among the molecules. However, detecting the enzyme-reactant interactions and associated conformati...

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Detalles Bibliográficos
Autores principales: Kim, Eugene, Baaske, Martin D., Schuldes, Isabel, Wilsch, Peter S., Vollmer, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5371424/
https://www.ncbi.nlm.nih.gov/pubmed/28435868
http://dx.doi.org/10.1126/sciadv.1603044