Analysis of Linear Antibody Epitopes on Factor H and CFHR1 Using Sera of Patients with Autoimmune Atypical Hemolytic Uremic Syndrome

INTRODUCTION: In autoimmune atypical hemolytic uremic syndrome (aHUS), the complement regulator factor H (FH) is blocked by FH autoantibodies, while 90% of the patients carry a homozygous deletion of its homolog complement FH-related protein 1 (CFHR1). The functional consequence of FH-blockade is wi...

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Detalles Bibliográficos
Autores principales: Trojnár, Eszter, Józsi, Mihály, Uray, Katalin, Csuka, Dorottya, Szilágyi, Ágnes, Milosevic, Danko, Stojanović, Vesna D., Spasojević, Brankica, Rusai, Krisztina, Müller, Thomas, Arbeiter, Klaus, Kelen, Kata, Szabó, Attila J., Reusz, György S., Hyvärinen, Satu, Jokiranta, T. Sakari, Prohászka, Zoltán
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5371605/
https://www.ncbi.nlm.nih.gov/pubmed/28424685
http://dx.doi.org/10.3389/fimmu.2017.00302

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5371605/
https://www.ncbi.nlm.nih.gov/pubmed/28424685
http://dx.doi.org/10.3389/fimmu.2017.00302

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