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The Calcium Channel C-Terminal and Synaptic Vesicle Tethering: Analysis by Immuno-Nanogold Localization

At chemical synapses the incoming action potential triggers the influx of Ca(2+) through voltage-sensitive calcium channels (CaVs, typically CaV2.1 and 2.2) and the ions binds to sensors associated with docked, transmitter filled synaptic vesicles (SVs), triggering their fusion and discharge. The Ca...

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Detalles Bibliográficos
Autores principales: Chen, Robert H. C., Li, Qi, Snidal, Christine A., Gardezi, Sabiha R., Stanley, Elise F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5371611/
https://www.ncbi.nlm.nih.gov/pubmed/28424589
http://dx.doi.org/10.3389/fncel.2017.00085