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Long-term brain structural magnetic resonance imaging and cognitive functioning in children treated for acute lymphoblastic leukemia with high-dose methotrexate chemotherapy alone or combined with CNS radiotherapy at reduced total dose to 12 Gy

INTRODUCTION: The aim of this study was to assess the long-term side effects of central nervous system prophylaxis (high-dose chemotherapy alone vs chemotherapy and CNS radiotherapy) according to the ALL IC-BFM 2002. METHODS: Thirty-tree children aged 6.7–19.9 years have been studied. The control gr...

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Detalles Bibliográficos
Autores principales: Zając-Spychała, Olga, Pawlak, Mikołaj A., Karmelita-Katulska, Katarzyna, Pilarczyk, Jakub, Derwich, Katarzyna, Wachowiak, Jacek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5371615/
https://www.ncbi.nlm.nih.gov/pubmed/28074235
http://dx.doi.org/10.1007/s00234-016-1777-8