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Treatment related toxicity in BRCA1-associated epithelial ovarian cancer – is DNA repairing impairment associated with more adverse events?

AIM OF THE STUDY: The presence of BRCA germline mutations in patients with ovarian cancer has been shown to have predictive and prognostic significance, including increased platinum-sensitivity. The aim of the study was to evaluate if patients with BRCA1-associated ovarian cancer have more treatment...

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Detalles Bibliográficos
Autores principales: Badora-Rybicka, Agnieszka, Budryk, Magdalena, Nowara, Elżbieta, Starzyczny-Słota, Danuta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5371704/
https://www.ncbi.nlm.nih.gov/pubmed/28373819
http://dx.doi.org/10.5114/wo.2016.64597