Cargando…

Treatment related toxicity in BRCA1-associated epithelial ovarian cancer – is DNA repairing impairment associated with more adverse events?

AIM OF THE STUDY: The presence of BRCA germline mutations in patients with ovarian cancer has been shown to have predictive and prognostic significance, including increased platinum-sensitivity. The aim of the study was to evaluate if patients with BRCA1-associated ovarian cancer have more treatment...

Descripción completa

Detalles Bibliográficos
Autores principales:	Badora-Rybicka, Agnieszka, Budryk, Magdalena, Nowara, Elżbieta, Starzyczny-Słota, Danuta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Termedia Publishing House 2016
Materias:	Original Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5371704/ https://www.ncbi.nlm.nih.gov/pubmed/28373819 http://dx.doi.org/10.5114/wo.2016.64597

Ejemplares similares

Neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio before chemotherapy as potential prognostic factors in patients with newly diagnosed epithelial ovarian cancer
por: Badora-Rybicka, Agnieszka, et al.
Publicado: (2016)

Unfavorable prognosis of nephroblastoma in adults
por: Huszno, Joanna, et al.
Publicado: (2013)

Adult Wilms’ tumor – diagnosis and current therapy
por: Huszno, Joanna, et al.
Publicado: (2013)

The risk factors of toxicity during chemotherapy and radiotherapy in breast cancer patients according to the presence of BRCA gene mutation
por: Huszno, Joanna, et al.
Publicado: (2015)

The influence of steroid receptor status on the cardiotoxicity risk in HER2-positive breast cancer patients receiving trastuzumab
por: Huszno, Joanna, et al.
Publicado: (2015)

Cardiac side effects of trastuzumab in breast cancer patients – single centere experiences
por: Huszno, Joanna, et al.
Publicado: (2013)

Spectrum of tumors in the families with Hereditary Breast Ovarian Cancer syndrome carrying germline mutations in BRCA1 and 2 genes
por: Budryk, M, et al.
Publicado: (2012)

The BRCA Gene in Epithelial Ovarian Cancer
por: Sánchez-Lorenzo, Luisa, et al.
Publicado: (2022)

BRCA immunohistochemistry for screening of BRCA mutation in epithelial ovarian cancer patients
por: Manchana, Tarinee, et al.
Publicado: (2020)

BRCA mutation in high grade epithelial ovarian cancers
por: Manchana, Tarinee, et al.
Publicado: (2019)

Germline mutations in BRCA1 and BRCA2 in epithelial ovarian cancer patients in Brazil
por: Maistro, Simone, et al.
Publicado: (2016)

Skin toxicity in BRAF(V600) mutated metastatic cutaneous melanoma patients treated with vemurafenib
por: Nowara, Elzbieta, et al.
Publicado: (2016)

Toxicity of (neo)adjuvant chemotherapy for BRCA1- and BRCA2-associated breast cancer
por: Drooger, Jan C., et al.
Publicado: (2016)

Prevalence and clinical characterization of BRCA1 and BRCA2 mutations in Korean patients with epithelial ovarian cancer
por: Paik, E Sun, et al.
Publicado: (2021)

BRCA1 promoter hypermethylation in sporadic epithelial ovarian carcinoma: Association with low expression of BRCA1, improved survival and co-expression of DNA methyltransferases
por: BAI, XUEFENG, et al.
Publicado: (2014)

Pre-operative high-dose-rate brachytherapy in early-stage cervical cancer: long-term single-center results
por: Kellas-Ślęczka, Sylwia, et al.
Publicado: (2022)

BRCA1 as a Therapeutic Target in Sporadic Epithelial Ovarian Cancer
por: Clark-Knowles, Katherine V., et al.
Publicado: (2010)

BRCA1 expression, proliferative and apoptotic activities in ovarian epithelial inclusions
por: Wang, Yiying, et al.
Publicado: (2017)

BRCA Mutations—The Achilles Heel of Breast, Ovarian and Other Epithelial Cancers
por: Loboda, Anna P., et al.
Publicado: (2023)

Reclassification of BRCA1 and BRCA2 variants found in ovarian epithelial, fallopian tube, and primary peritoneal cancers
por: Ha, Hyeong In, et al.
Publicado: (2020)

New paradigms for BRCA1/BRCA2 testing in women with ovarian cancer: results of the Genetic Testing in Epithelial Ovarian Cancer (GTEOC) study
por: Plaskocinska, Inga, et al.
Publicado: (2016)

BRCA1 Regulates Follistatin Function in Ovarian Cancer and Human Ovarian Surface Epithelial Cells
por: Karve, Tejaswita M., et al.
Publicado: (2012)

The potential role of miRNAs in therapy of breast and ovarian cancers associated with BRCA1 mutation
por: Strumidło, Agnieszka, et al.
Publicado: (2017)

Dermoscopic assessment of skin toxicities in patients with melanoma during treatment with vemurafenib
por: Rajczykowski, Marcin, et al.
Publicado: (2018)

Polygenic risk scores and breast and epithelial ovarian cancer risks for carriers of BRCA1 and BRCA2 pathogenic variants
por: Barnes, Daniel R., et al.
Publicado: (2020)

MK-2206 sensitizes BRCA-deficient epithelial ovarian adenocarcinoma to cisplatin and olaparib
por: Whicker, Margaret E., et al.
Publicado: (2016)

Metaplastic breast carcinomas – analysis of prognostic factors in a case series
por: Nowara, Elżbieta, et al.
Publicado: (2014)

BRCA and lynch syndrome-associated ovarian cancers behave differently
por: Ryan, Neil A.J., et al.
Publicado: (2017)

Beyond Breast and Ovarian Cancers: PARP Inhibitors for BRCA Mutation-Associated and BRCA-Like Solid Tumors
por: O’Sullivan, Ciara C., et al.
Publicado: (2014)

Genome-Wide Gene Expression Analyses of BRCA1- and BRCA2-Associated Breast and Ovarian Tumours
por: Wiggins, George A. R., et al.
Publicado: (2020)

Reliability of Tumor Testing Compared to Germline Testing for Detecting BRCA1 and BRCA2 Mutations in Patients with Epithelial Ovarian Cancer
por: Bekos, Christine, et al.
Publicado: (2021)

Frequency of BRCA1 and BRCA2 causative founder variants in ovarian cancer patients in South-East Poland
por: Kluz, Tomasz, et al.
Publicado: (2018)

Young Israeli women with epithelial ovarian cancer: prevalence of BRCA mutations and clinical correlates
por: Helpman, Limor, et al.
Publicado: (2017)

BRCA-Associated Ovarian Cancer: From Molecular Genetics to Risk Management
por: Girolimetti, Giulia, et al.
Publicado: (2014)

Association between Olaparib Exposure and Early Toxicity in BRCA-Mutated Ovarian Cancer Patients: Results from a Retrospective Multicenter Study
por: Velev, Maud, et al.
Publicado: (2021)

Chemotherapy for gastric cancer patients – time for personalization in medicine?
por: Nowara, Elżbieta, et al.
Publicado: (2012)

Prognostic factors in Polish patients with BRCA1-dependent ovarian cancer
por: Szatkowski, Wiktor, et al.
Publicado: (2016)

Progression-free survival and overall survival after BRCA1/2-associated epithelial ovarian cancer: A matched cohort study
por: Heemskerk-Gerritsen, Bernadette A. M., et al.
Publicado: (2022)

The role of the breast cancer susceptibility gene 1 (BRCA1) in sporadic epithelial ovarian cancer
por: McCoy, Marcia L, et al.
Publicado: (2003)

Germline and Somatic BRCA1/2 Mutations in 172 Chinese Women With Epithelial Ovarian Cancer
por: You, Yan, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_4s01nmnp9hrrg05v374i6m4gvh