Suppression of FOXM1 Transcriptional Activities via a Single-Stranded DNA Aptamer Generated by SELEX

The transcription factor FOXM1 binds to its consensus sequence at promoters through its DNA binding domain (DBD) and activates proliferation-associated genes. The aberrant overexpression of FOXM1 correlates with tumorigenesis and progression of many cancers. Inhibiting FOXM1 transcriptional activiti...

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Detalles Bibliográficos
Autores principales: Xiang, Qin, Tan, Guixiang, Jiang, Xia, Wu, Kuangpei, Tan, Weihong, Tan, Yongjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5371818/
https://www.ncbi.nlm.nih.gov/pubmed/28358012
http://dx.doi.org/10.1038/srep45377

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5371818/
https://www.ncbi.nlm.nih.gov/pubmed/28358012
http://dx.doi.org/10.1038/srep45377

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