Acute Oral Toxicity of Tetrodotoxin in Mice: Determination of Lethal Dose 50 (LD50) and No Observed Adverse Effect Level (NOAEL)

Tetrodotoxin (TTX) is starting to appear in molluscs from the European waters and is a hazard to seafood consumers. This toxin blocks sodium channels resulting in neuromuscular paralysis and even death. As a part of the risk assessment process leading to a safe seafood level for TTX, oral toxicity d...

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Detalles Bibliográficos
Autores principales: Abal, Paula, Louzao, M. Carmen, Antelo, Alvaro, Alvarez, Mercedes, Cagide, Eva, Vilariño, Natalia, Vieytes, Mercedes R., Botana, Luis M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5371830/
https://www.ncbi.nlm.nih.gov/pubmed/28245573
http://dx.doi.org/10.3390/toxins9030075

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5371830/
https://www.ncbi.nlm.nih.gov/pubmed/28245573
http://dx.doi.org/10.3390/toxins9030075

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