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Invariant Chain Complexes and Clusters as Platforms for MIF Signaling
Invariant chain (Ii/CD74) has been identified as a surface receptor for migration inhibitory factor (MIF). Most cells that express Ii also synthesize major histocompatibility complex class II (MHC II) molecules, which depend on Ii as a chaperone and a targeting factor. The assembly of nonameric comp...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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MDPI
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5371871/ https://www.ncbi.nlm.nih.gov/pubmed/28208600 http://dx.doi.org/10.3390/cells6010006 |